Anti-HIV1 Nef Antibody

The Antibodies.com Anti-HIV1 Nef Antibody is a rabbit polyclonal reagent raised against the Nef accessory protein of Human Immunodeficiency Virus type 1. HIV-1 Nef is a roughly 27 kDa myristoylated, membrane-associated accessory protein produced early in the viral replication cycle. It plays a critical role in immune evasion by downregulating CD4 and MHC class I molecules from the surface of infected cells, and it enhances viral infectivity and replication.

This unconjugated IgG reagent is supplied as a liquid formulation in a 100 µl volume and is validated for Western blot (WB), dot blot (DB), immunoprecipitation (IP), and ELISA applications. It supports research into viral pathogenesis, host-pathogen interactions, and therapeutic strategies targeting HIV-1. For long-term stability, store the antibody refrigerated and avoid repeated freeze-thaw cycles by preparing small aliquots before use.