Anti-Histone H4 Antibody

Histone H4 is a core component of the nucleosome, and antibodies raised against it underpin a wide swath of chromatin, epigenetics, and gene regulation research. This unconjugated rabbit polyclonal reagent from Antibodies.com has been validated for Western blot, immunohistochemistry, immunofluorescence, and ELISA workflows, giving laboratories flexibility across imaging and biochemical readouts.

Demonstrated reactivity spans human, mouse, rat, and monkey samples, supporting comparative studies in cell line panels, primary tissue, and primate-derived models. The antibody is supplied in a 50 µl volume, sufficient for screening multiple conditions or running pilot optimization before scaling up.

Researchers commonly apply it when probing histone acetylation and methylation states, mapping nucleosome positioning, or characterizing chromatin remodeler activity. For best results, aliquot upon arrival and store refrigerated, avoiding repeated freeze-thaw cycles to maintain epitope recognition across downstream Western blot, immunofluorescence, and immunohistochemistry experiments.