Anti-Histone H4 Antibody

Affinity-purified polyclonal reagent from Antibodies.com targets Histone H4, a core component of the nucleosome that packages genomic DNA into chromatin. Raised in rabbit and supplied as an unconjugated 100 µl aliquot, the antibody supports chromatin biology, epigenetics, and gene regulation workflows across immunoblotting, immunohistochemistry, immunofluorescence, and ELISA assays. It has been validated for reactivity with human, mouse, rat, and monkey samples, enabling translational studies from rodent models to primate tissue and conserved mammalian epitopes. Researchers commonly use this reagent to probe post-translational modifications on the H4 tail, including acetylation and methylation marks that correlate with active transcription, as well as bulk H4 levels in chromatin fractionation experiments. Storage at 4 °C is appropriate for short-term use, while longer term storage at -20 °C in working aliquots helps preserve activity and limit freeze-thaw cycles. Each lot is supplied as a single vial ready for dilution into appropriate assay buffers.