Anti-Histone H3 (Tri-Methyl K79) Antibody

Affinity‑purified from rabbit serum by antigen‑affinity chromatography, this polyclonal reagent from Antibodies.com is raised against a synthetic tri‑methylated peptide centred on lysine 79 of human histone H3 and selectively detects the H3K79me3 mark. Supplied as 50 µl of unconjugated IgG at 1 mg/ml in PBS containing 0.1% sodium azide and 50% glycerol, the antibody is validated for chromatin studies as well as standard immunoassays and performs reliably across Western blot, immunohistochemistry, immunofluorescence, immunoprecipitation, ChIP and ChIP‑seq workflows. Reactivity has been confirmed on human, mouse and rat samples, with the target histone running at the expected ~17 kDa molecular weight. The reagent is shipped on cold packs; for long‑term use, aliquot and store at –20 °C, avoiding repeated freeze/thaw cycles to preserve lot‑specific titre and affinity. Researchers investigating epigenetic regulation, transcription‑coupled chromatin states or Dot Blot‑based methyl‑mark screening will find this reagent a robust, multi‑application tool for profiling tri‑methyl histone H3 (Lys79) occupancy.