Anti-Histone H3 (phospho T11) Antibody

Raised in rabbit as a polyclonal IgG preparation, this unconjugated primary antibody from Antibodies.com targets Histone H3 phosphorylated at threonine 11, a chromatin mark associated with mitotic entry, transcriptional control, and stress-induced chromatin remodeling. The reagent is supplied as a 200 µL liquid aliquot and is validated for Western blot detection of the modified histone in lysates from human, mouse, and rat samples.

Because the reagent is selective for the phospho-T11 epitope rather than total Histone H3, it supports side-by-side comparisons of modified versus unmodified H3 pools in nuclear extracts, acid-extracted histones, or whole-cell lysates from dividing cultures. The unconjugated IgG format allows researchers to pair it with secondary antibodies of their choice for chemiluminescent or fluorescent Western blot readouts. For best results, store refrigerated in working aliquots and limit freeze-thaw cycles to preserve antibody activity across repeated experiments.