Anti-Histone H3 Antibody

Histone H3 is one of the four core histone proteins that package genomic DNA into nucleosomes, making antibodies against this target a cornerstone reagent in chromatin biology and epigenetics research. This unconjugated rabbit polyclonal reagent from Antibodies.com is raised against Histone H3 and validated for Western blot and ELISA workflows across human, mouse, and rat samples.

Supplied at 100 µl per vial, the antibody is offered as a research-use-only reagent for detection of endogenous Histone H3 in cell lysates, nuclear extracts, and histone preparations. Its polyclonal format provides broad epitope coverage, useful when probing total Histone H3 levels or serving as a loading control alongside studies of post-translational modifications such as methylation, acetylation, and phosphorylation.

The unconjugated format allows flexibility for downstream labeling with HRP, fluorophore, or biotin conjugates tailored to the assay design. For handling, aliquoting upon arrival is recommended to limit freeze-thaw cycles and preserve antibody activity across multiple experiments.