Anti-Histone H3 Antibody

A mouse-derived monoclonal reagent that targets the core nucleosome protein Histone H3, supplied unconjugated by Antibodies.com for chromatin biology, epigenetics, and nuclear fraction analyses. Histone H3 is one of four canonical histones (H3, H4, H2A, H2B) assembled into the octameric core around which genomic DNA is wrapped, and it carries post-translational modifications widely studied in gene regulation research.

Validated for western blot, immunofluorescence, and immunoprecipitation, the antibody reacts with human, rat, and mouse samples, supporting cross-species work in cell lines, primary cultures, and tissue-derived lysates. In western blot applications it is frequently deployed as a chromatin loading control, allowing normalization of nuclear extracts against a stable, abundant nuclear marker.

Each vial delivers 100 µl of unconjugated antibody, giving researchers flexibility to pair it with HRP-, fluorophore-, or biotin-conjugated secondary reagents matched to their preferred detection platform. Store refrigerated and protect from light to preserve activity across repeated use.