Anti-Histone H3 Antibody

The Antibodies.com rabbit polyclonal anti-Histone H3 antibody is an unconjugated primary antibody supplied as 100 µl of polyclonal serum raised in rabbit. It targets histone H3, a core component of the nucleosome around which DNA is wrapped, and is validated for use in western blot (WB), immunohistochemistry (IHC), and ELISA workflows.

This reagent is reactive against human, mouse, and rat samples, making it broadly applicable across common model organisms and human tissue research. As a polyclonal preparation, the antibody recognizes multiple epitopes on the histone H3 protein, which can improve signal in chromatin and nuclear extracts where the target may be partially modified.

For typical use, store the vial refrigerated and protect from light; aliquoting is recommended to limit freeze-thaw cycles. The unconjugated format allows researchers to pair the antibody with custom secondary conjugates — HRP, fluorophores, or biotin — depending on the detection method required. The product is supplied by Antibodies.com as a primary antibody for research use only.