Anti-Histone H3 (Acetyl-K18) Antibody

Raised in rabbit and affinity-purified, this polyclonal reagent from Antibodies.com selectively detects histone H3 acetylated at lysine 18, a chromatin mark linked to active transcription and epigenetic regulation.

The unconjugated antibody is supplied at 1 mg/ml in phosphate buffered saline (pH 7.2) containing 0.05% sodium azide, and is packaged as a 100 µl vial ready to aliquot for western blot, immunohistochemistry, and immunofluorescence workflows.

Reactivity has been validated on human, mouse, and rat samples, supporting comparative work in primary cells, tissue cryosections, and fixed whole-mount preparations where researchers need to localize H3K18ac at promoters, nuclear bodies, or during cell cycle transitions.

Polyclonal recognition of the acetylated epitope across multiple flanking peptide contexts helps when mapping acetylation dynamics in cancer cell lines, neuronal differentiation models, and chromatin remodeling studies.

For research use only; keep refrigerated upon arrival and aliquot the stock to limit repeated freeze-thaw cycles of the working solution.