Anti-Histone H3 (A7) Antibody

A rabbit-derived polyclonal reagent raised against the conserved Histone H3 (A7) epitope, supplied by Antibodies.com as an unconjugated primary antibody optimized for immunohistochemistry workflows. The antibody is provided at 1 mg/ml in a phosphate buffered saline (PBS) carrier containing 0.05% sodium azide at approximately pH 7.2, and is dispensed in a 100 µl vial suitable for routine lab use. Target reactivity has been validated on Human, Mouse, and Rat tissue sections, making this reagent useful for chromatin and nuclear staining studies across standard mammalian model systems.

Researchers commonly apply it to probe histone methylation, acetylation, and chromatin remodeling contexts where H3 abundance is used as a normalization or structural reference signal in IHC. The polyclonal format offers broader epitope coverage than monoclonal alternatives, which can help when mapping modified H3 variants in tissue sections. Refrigerate the vial upon receipt and protect from light to preserve antibody activity, and note that the sodium azide preservative inhibits microbial growth in the working solution. Intended for research use only, this reagent supports laboratory investigations of epigenetic markers in fixed tissue specimens.