Anti-Histone H3.3 Antibody

Histone H3.3 is a replication-independent histone variant deposited at active promoters, enhancers, and telomeric regions, where it serves as a marker of transcriptionally active chromatin. This rabbit polyclonal antibody from Antibodies.com was raised against the H3.3 variant and selectively recognizes H3.3 in chromatin preparations and fixed cells, supporting research into gene regulation, epigenetics, telomere maintenance, and chromatin remodeling.

Validation covers Western blot, immunohistochemistry, immunofluorescence, and ELISA workflows. The unconjugated IgG is supplied as 100 µl of polyclonal antiserum in a single vial and has been confirmed reactive against human, mouse, and rat samples, enabling cross-species studies in cell-based and tissue-based experiments.

For routine handling, store the vial at -20 °C in small aliquots to limit freeze-thaw cycles, and protect from light during short-term bench use. Research use only.