Anti-Histone H2A.X (Ab-139) Antibody

Detect and characterize histone H2A.X, the chromatin-associated histone variant that becomes phosphorylated at Ser139 (γH2A.X) during the cellular DNA damage response, with this rabbit polyclonal antibody from Antibodies.com. Raised against an epitope flanking residue 139 of the human protein, the reagent is supplied as 100 µl of unconjugated antiserum validated for western blot, immunohistochemistry, and immunofluorescence on human samples. Investigators working on double-strand break repair, radiation biology, genotoxicity screening, or chromatin remodeling apply it to monitor H2A.X expression and γH2A.X foci formation across cell lines and fixed tissue sections. The polyclonal composition recognizes a broader span of epitopes than a typical monoclonal reagent, supporting detection of both unmodified and post-translationally modified H2A.X. Aliquot on receipt and store at -20°C, limiting freeze-thaw cycles to preserve antibody titer over long-term use.