Anti-Histone H2A (Hydroxyl-Y39) Antibody

Recombinant rabbit monoclonal antibody from Antibodies.com specifically recognizes hydroxylated tyrosine 39 (Y39) on histone H2A, a post-translational modification linked to chromatin remodeling, oxidative stress responses, and DNA damage signaling. Provided as a 100 µl aliquot in TBS buffer (pH 7.4) with 1% BSA, 40% glycerol, and 0.05% sodium azide as preservative, this unconjugated primary antibody is validated for Western blot (WB) and immunohistochemistry (IHC) applications across human, mouse, and rat samples.

The recombinant production approach supports batch-to-batch consistency and reproducibility, while the rabbit monoclonal format delivers targeted recognition of this low-abundance PTM. For long-term integrity, aliquot the reagent and store at -20°C, protect from light, and avoid repeated freeze-thaw cycles. The H2A Y39 hydroxyl mark has been investigated in studies of nuclear hormone signaling, oxidative DNA damage, and chromatin dynamics, making this reagent a useful tool for epigenetics, DNA damage response, and chromatin biology research. The antibody is supplied in a vial as a liquid preparation compatible with standard immunodetection workflows.