Anti-HIST2H3A Antibody

Raised in rabbit against the human HIST2H3A protein, this polyclonal IgG reagent from Antibodies.com targets Histone H3.2, a replication-dependent histone H3 variant incorporated into nucleosomes during chromatin assembly in S-phase. The antibody is unconjugated and supplied as a 200 µL vial, validated for Western blot detection of endogenous HIST2H3A in human cell and tissue lysates. The host isotype is IgG, and the reagent supports basic investigations of histone deposition and chromatin-associated changes in human-derived samples.

For routine handling, aliquot upon arrival to limit freeze-thaw cycles, store refrigerated for short-term use or frozen at -20°C for longer-term retention, and protect from light to preserve the unconjugated IgG. As a polyclonal reagent, the antibody recognizes multiple epitopes across the Histone H3.2 target, useful when probing variant-specific histone levels in human chromatin preparations and when comparing replicative histone deposition against other H3 family members.