Anti-HIST2H2AA4 Antibody

The HIST2H2AA4 protein is a replication-dependent histone H2A variant encoded on chromosome 1q21.2, contributing to nucleosome assembly and chromatin packaging during S-phase transcription. Antibodies.com offers this reagent as a rabbit polyclonal IgG preparation supplied at 200 µl, unconjugated and validated for Western blot detection of the endogenous human target in cell lysates and acid-extracted nuclear fractions. Researchers investigating histone stoichiometry, post-translational modification mapping, or chromatin remodeling pathways can resolve this approximately 14 kDa protein on standard SDS-PAGE immunoblots using HRP- or fluorophore-conjugated secondary reagents. The polyclonal format increases the probability of recognizing multiple epitopes, supporting reproducible band detection across a range of human cell lines and primary tissue samples. Aliquot upon receipt, store refrigerated at 4 degrees C, and avoid repeated freeze-thaw cycles to preserve antibody activity for ongoing chromatin and epigenetics research.