Anti-HIF1AN Antibody

HIF1AN (Hypoxia Inducible Factor 1 Alpha Subunit Inhibitor), also known as FIH-1, is an asparaginyl hydroxylase that downregulates the transcriptional activity of HIF-1α under normoxic conditions, making it a central regulator of oxygen sensing and the cellular hypoxia response. This rabbit polyclonal reagent from Antibodies.com is supplied as an unconjugated preparation in a 100 µl volume and is raised against the human HIF1AN target. The antibody has been validated for western blot and immunohistochemistry workflows, supporting detection of endogenous FIH-1 protein in cell lysates and tissue sections. Its polyclonal format, with documented reactivity toward human antigen, allows flexible use across signaling, cancer biology, and hypoxia-pathway studies where researchers need to probe FIH-1 expression alongside HIF-1α itself. Recommended storage is at -20 °C in working aliquots to preserve antibody activity through multiple freeze-thaw cycles, and the unconjugated format enables pairing with secondary antibodies of the researcher's choice for custom detection chemistries.