Anti-HIF1AN Antibody

A polyclonal antibody targeting HIF1AN (also known as Factor Inhibiting HIF-1, FIH-1), the asparaginyl hydroxylase that post-translationally modifies HIF-1α on Asn803 under normoxic conditions to suppress hypoxia-response transcription. This unconjugated rabbit polyclonal reagent from Antibodies.com recognizes the human, mouse, and rat protein and is supplied at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol as a 100 µl vial. Verified applications span western blot, immunohistochemistry, immunofluorescence, immunoprecipitation, and chromatin immunoprecipitation, enabling studies of oxygen-sensing pathways, HIF signaling crosstalk, and chromatin association of this key HIF regulator. The polyclonal format provides multi-epitope recognition of endogenous FIH-1 in cell lysates, fixed tissue sections, and native chromatin complexes, supporting research into angiogenesis, cancer metabolism, and ischemic response models.