Anti-HGK (R430) Antibody

Raised in rabbit against the HGK kinase, this unconjugated polyclonal antibody targets an epitope surrounding residue R430 of the protein also known as MAP4K4, a serine/threonine kinase implicated in JNK pathway signaling, cytoskeletal remodeling, and inflammatory responses. The reagent is supplied by Antibodies.com as a 50 µl aliquot at 1 mg/ml in phosphate buffered saline with 0.05% sodium azide at approximately pH 7.2, a buffer combination that supports refrigerated storage while preventing microbial contamination. Validated applications include Western blot for detecting endogenous kinase levels across lysates and immunofluorescence for visualizing subcellular distribution in fixed cells. Cross-reactivity is confirmed against human, mouse, and rat samples, supporting comparative studies in cell line panels and primary tissue. Researchers investigating MAP4K4 function in macrophage activation, endothelial migration, or stress-activated kinase cascades rely on this reagent, and the unconjugated format permits flexible selection of secondary labels for multiplex imaging or custom detection chemistries.