Anti-HGK (R430) Antibody

Raised in rabbit and supplied as 100 µl at 1 mg/ml, this polyclonal antibody from Antibodies.com recognises MAP4K4 (also referred to as HGK), a serine/threonine kinase of the STE20 family that participates in TNF-driven inflammatory signalling, cytoskeletal regulation, and stress-activated kinase cascades. The immunogen corresponds to a region surrounding residue R430 of the human MAP4K4 sequence, and the reagent is provided in phosphate buffered saline (PBS) containing 0.05% sodium azide at approximately pH 7.2.

Validated for western blot (WB) and immunofluorescence (IF), the unconjugated antibody cross-reacts with human, mouse, and rat samples, supporting comparative studies across in vitro and in vivo model systems. Laboratories investigating cardiovascular remodelling, endothelial dysfunction, metabolic inflammation, and tumour cell invasion use this reagent to probe MAP4K4 expression and downstream activity. The unconjugated format allows flexible pairing with HRP, Alexa Fluor, or biotin secondary reagents, and the inclusion of sodium azide as a preservative supports short-term storage at 4 °C, with appropriate care taken when the antibody is used in azide-sensitive HRP detection workflows.