Anti-Hexokinase-2 Antibody

This rabbit polyclonal antibody from Antibodies.com specifically targets Hexokinase-2, the 102 kDa mitochondrial-bound glycolytic enzyme that catalyzes the committed step of glucose phosphorylation and is frequently upregulated in tumors exhibiting the Warburg effect. Supplied as 100 µl of a 1 mg/ml stock in PBS with 0.1% sodium azide and 50% glycerol, the unconjugated reagent is validated for western blot, immunohistochemistry, and immunofluorescence workflows. Reactivity has been confirmed against human, mouse, and rat samples, making the antibody useful across a broad spectrum of cancer metabolism, metabolic disorder, and cell signaling studies where HK2 expression, mitochondrial association, or glycolytic flux are being investigated. Aliquot upon arrival and store refrigerated to preserve activity across multiple freeze-thaw cycles; the glycerol-based formulation also permits storage at -20 °C for long-term archiving of working stocks while minimizing degradation of the immunoglobulin.