Anti-HEXIM1 Antibody

Manufactured by Antibodies.com, this Rabbit polyclonal reagent targets HEXIM1 (hexamethylene bisacetamide-inducible protein 1) and is supplied as a 50 µL aliquot at a working concentration of 1.0 mg/mL. The antibody was raised against a recombinant human HEXIM1 immunogen and affinity-purified using that immunogen, ensuring recognition of the endogenous total HEXIM1 protein. It is unconjugated, which makes it suitable for downstream labelling with the user's preferred reporter, and is buffered in phosphate-buffered saline (without Mg²⁺ and Ca²⁺) at pH 7.4, containing 150 mM NaCl, 0.02% sodium azide, and 50% glycerol as a cryoprotectant. The host species is Rabbit, the clonality is polyclonal, and recommended applications include Western Blot (WB), Immunohistochemistry (IHC), and Immunocytochemistry/Immunofluorescence (ICC/IF). According to the supplier's validation data, the reagent has been confirmed to react with Human and Rat samples. For handling, the vial is shipped at 4 °C; on receipt, users should aliquot and store it at -20 °C, taking care to avoid repeated freeze/thaw cycles, which can compromise antibody integrity. The product is intended for research use only and is not validated for diagnostic or therapeutic applications. Researchers investigating transcriptional regulation by the 7SK small nuclear ribonucleoprotein complex, where HEXIM1 functions as a key inhibitor of positive transcription elongation factor b (P-TEFb), will find this reagent useful for probing HEXIM1 expression and localisation across a variety of cell and tissue contexts.