Anti-HET / SAF B Antibody

Raised in rabbit and supplied at 100 µl, this unconjugated polyclonal antibody from Antibodies.com recognizes the HET / SAF-B target on human samples. The reagent is validated for Western blot (WB) and immunofluorescence (IF) workflows, supporting detection of native and denatured protein across cell lysate and fixed-cell preparations. SAF-B acts as a scaffold attachment factor that anchors chromatin loop domains to the nuclear matrix and modulates transcription of hormone-responsive genes, so the antibody serves research programs in chromatin architecture, nuclear organization, and steroid-receptor signaling studies. Polyclonal sera typically present multiple epitope specificities, which can improve signal robustness in blotting and imaging assays. The unconjugated format leaves the choice of reporter label and detection chemistry to the end user, which is helpful when pairing the primary reagent with custom fluorophore or enzyme conjugates for multiplexed imaging or chromogenic readouts.