Anti-Hepatitis C Virus NS3 Antibody [20-8] - Identical to Thermo (MA1-21376)

This mouse IgG1 monoclonal antibody, clone 20-8, targets the non-structural protein 3 (NS3) of human Hepatitis C virus and is supplied by Antibodies.com as a lyophilised 100 µg vial. The unconjugated reagent is validated for ELISA and Western blot applications, supporting sensitive detection of NS3 antigen in recombinant protein samples and transfected cell lysates.

Because NS3 functions as both a serine protease and an RNA helicase within the viral replication complex, a monoclonal capture reagent directed against this antigen gives researchers a consistent, batch-to-batch tool for tracking viral protein expression. The lyophilised presentation preserves activity during refrigerated storage and allows reconstitution to the desired working concentration immediately before each assay. The 20-8 clone is widely referenced in published HCV research and is noted as identical to a well-known Thermo reagent, making it straightforward to integrate into established protocols.

Typical use cases include immunoblotting of HCV replicon systems, characterization of antiviral compounds that disrupt NS3 protease function, and supporting diagnostic assay development where a defined monoclonal reagent is required. Each vial is intended for research use only, and the unconjugated IgG1 format offers flexibility for downstream labelling with HRP, biotin, or fluorophore conjugates according to the experimental design.