Anti-Hepatitis B Core Antigen (HBcAg) Antibody

Produced by Antibodies.com as a primary antibody reagent for hepatitis B virus research, this mouse monoclonal antibody binds the Hepatitis B Core Antigen (HBcAg), the nucleocapsid protein that packages the viral genome and drives core particle assembly inside infected hepatocytes. The antibody is supplied as a 1 mg vial of Protein A purified immunoglobulin in unconjugated form, with an IgG2b isotype that supports consistent secondary antibody selection across immunodetection workflows.

Validated for ELISA and western blot, the reagent supports serological profiling of HBcAg expression in recombinant antigen preparations, transfected cell lysates, and recombinant core particle studies. Its unconjugated format lets researchers conjugate it directly to HRP, biotin, or fluorophores of choice, and the Protein A purification step removes contaminating serum proteins that could elevate background in downstream assays.

For handling, the vial should be stored refrigerated and aliquoted on first use to minimize freeze-thaw cycles that degrade binding activity over time. Laboratories studying HBV replication, capsid assembly, antiviral screening, or diagnostic assay development pair this reagent with anti-HBsAg and anti-HBeAg matched reagents to map the full serological profile.