Anti-HELLS Antibody

HELLS (also known as LSH or SMARCA6) is a lymphoid-specific chromatin remodeler that supports DNA methylation maintenance and heterochromatin formation across mammalian genomes. This rabbit polyclonal antibody from Antibodies.com is raised against HELLS and validated for western blot, immunohistochemistry, immunofluorescence, immunoprecipitation, and chromatin immunoprecipitation assays, with reactivity confirmed against human samples. The unconjugated format allows pairing with custom secondary reagents for fluorescence, enzymatic, or bead-based detection, and the 100 µl volume supports multiple replicate experiments across these workflow types. HELLS has documented roles in transcriptional silencing, lymphoid lineage commitment, DNA repair, and genome stability, making this reagent well suited for epigenetic studies of hematopoiesis, stem cell pluripotency, and tumor biology where methylation patterning and chromatin accessibility are central questions. Shipped as a liquid polyclonal reagent intended for research use only, it integrates into standard immunodetection protocols used in chromatin and gene regulation research laboratories.