Anti-HELLS Antibody

The polyclonal reagent targets HELLS (also known as LSH or SMARCA6), a SNF2-family chromatin-remodeling ATPase central to DNA methylation patterning, transcriptional silencing, and lymphoid maturation. Raised in rabbit and validated for western blot, immunohistochemistry, immunofluorescence, immunoprecipitation, and chromatin immunoprecipitation, this Antibodies.com reagent recognizes human, mouse, and rat samples. The unconjugated antibody is provided as a 100 µl liquid aliquot at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol. Investigators working in developmental epigenetics, chromatin-remodeling biology, hematopoietic lineage studies, and tumor epigenetics use it to track HELLS expression and recruitment across gene-regulatory regions.