Anti-HDAC6 Antibody

Affinity-purified polyclonal reagent raised in rabbit against HDAC6 (Histone Deacetylase 6), a cytoplasmic class IIb deacetylase involved in aggresome formation, microtubule acetylation, and chaperone regulation. Antibodies.com supplies this unconjugated preparation at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, packaged as 100 µl per vial and validated across western blot, immunohistochemistry, and immunofluorescence workflows with human, mouse, and rat specimens. HDAC6 catalyzes removal of acetyl groups from substrates such as α-tubulin, HSP90, and cortactin, so the antibody supports investigations of cytoskeletal dynamics, autophagy flux, and proteotoxic-stress responses relevant to cancer biology and neurodegeneration research. The unconjugated format gives flexibility for direct labeling or pairing with anti-rabbit HRP and fluorophore conjugates in chromogenic, fluorescence, and tyramide signal amplification workflows.