Anti-HDAC5 Antibody

HDAC5 is a class IIa histone deacetylase that regulates gene expression through chromatin remodeling, and this rabbit polyclonal IgG antibody from Antibodies.com targets the human protein for detection in research western blot and immunohistochemistry workflows. The unconjugated reagent is supplied as a 200 µl liquid aliquot of polyclonal serum raised in rabbit, and it specifically recognizes HDAC5 in human samples.

Class IIa HDAC family members shuttle between the nucleus and cytoplasm in response to phosphorylation events triggered by calcium and calmodulin-dependent kinase signaling pathways. HDAC5 in particular governs cardiac hypertrophy, neuronal survival programs, and stress-responsive transcription factors such as MEF2, and researchers studying these regulatory circuits use this antibody to map expression patterns in tissue sections by immunohistochemistry and to monitor protein levels in cell lysates by western blotting.

The host species is rabbit, the clonality is polyclonal, and the immunoglobulin class is IgG, providing multi-epitope recognition across the target. The reagent is intended for research use only and should be refrigerated until first use, with smaller working aliquots recommended to preserve antibody stability across repeated freeze-thaw cycles.