Anti-HDAC4 Antibody

HDAC4 (Histone Deacetylase 4) is a class IIa deacetylase that shuttles between the nucleus and cytoplasm, regulating chromatin remodeling and signal-dependent transcription in muscle, neuronal, and cardiac lineages. This mouse monoclonal reagent from Antibodies.com is supplied as a 100 µl aliquot of unconjugated IgG2a, raised against HDAC4 for use in standard immunodetection workflows. It is validated for western blot and immunocytochemistry, and reacts with human, mouse, and rat samples, enabling comparative studies across model organisms and primary cells. Typical applications include probing HDAC4-dependent regulation of MEF2-driven transcription, mapping subcellular redistribution under stress or differentiation cues, and tracking expression changes in development and disease models linked to altered acetylation. For best results, aliquot on receipt to limit freeze-thaw cycles, store frozen at -20 °C, and protect the vial from light.