Anti-HDAC4 Antibody

Produced in rabbit and supplied at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, this unconjugated polyclonal reagent from Antibodies.com targets HDAC4, a class IIa histone deacetylase implicated in chromatin remodeling, transcriptional repression, and the regulation of muscle, neuronal, and metabolic gene programs. The 100 µl aliquot is validated for Western blot, immunohistochemistry, immunofluorescence, immunoprecipitation, and chromatin immunoprecipitation workflows, and the antibody cross-reacts with human, mouse, and rat orthologues, supporting comparative studies across standard model systems. Researchers investigating cardiac hypertrophy, skeletal muscle differentiation, neuronal survival pathways, or HDAC4-driven tumor biology can apply the reagent to cell lysates, fixed tissue sections, and chromatin preparations. For best stability, aliquot upon arrival and store at -20 °C in single-use portions, avoiding repeated freeze-thaw cycles. Sodium azide is included as a preservative; the conjugate is unconjugated, allowing users to pair the antibody with their own secondary detection reagents and label chemistries.