Anti-HDAC4 Antibody

This rabbit polyclonal IgG antibody targets HDAC4 (Histone Deacetylase 4), a class IIa chromatin-modifying enzyme studied for its role in transcriptional repression, neuronal survival pathways, and cardiac hypertrophy models. From Antibodies.com, the unconjugated reagent is supplied as 100 µl of liquid and is validated for Western blot, immunofluorescence, and immunohistochemistry workflows. Cross-reactivity has been confirmed with Human, Mouse, and Rat samples, making it useful for comparative studies across rodent and human cell lines, primary neurons, and tissue sections. The polyclonal format supports detection of multiple HDAC4 epitopes, which can be helpful when studying post-translational modifications, nuclear-cytoplasmic shuttling, or proteolytic cleavage patterns. Researchers commonly apply this reagent in chromatin remodeling studies, signal transduction investigations, and disease model research where altered HDAC4 expression or subcellular localization is implicated. Storage at -20 °C in working aliquots helps preserve activity through repeated freeze-thaw cycles, and the unconjugated format allows flexible pairing with custom fluorophores, biotin, or HRP secondary reagents. For research use only.