Anti-HDAC3 (Y414) Antibody

Raised in rabbit against histone deacetylase 3, this polyclonal antibody specifically recognizes HDAC3 phosphorylated at tyrosine 414, a site targeted by Src-family kinases and implicated in regulating HDAC3 enzymatic activity and co-repressor recruitment. Distributed by Antibodies.com as a 50 µl single-use vial at 1 mg/ml in phosphate buffered saline (pH 7.2) with 15 mM sodium azide, the unconjugated reagent supports Western blot, immunohistochemistry, and immunofluorescence detection in human, mouse, and rat samples. Investigators working on chromatin remodeling, transcriptional repression, or signaling networks that involve phospho-Y414 HDAC3 can use it to track phosphorylation-dependent changes in expression or subcellular localization. Store the vial refrigerated and protect from light; aliquot if needed and limit freeze-thaw cycles to preserve binding performance.