Anti-HDAC2 Antibody

Raised in rabbit against Histone Deacetylase 2 (HDAC2), this unconjugated polyclonal reagent from Antibodies.com is validated for Western blot, immunohistochemistry, and immunofluorescence workflows on human and mouse samples. HDAC2 is a class I lysine deacetylase that operates within NuRD and Sin3A corepressor complexes to remodel chromatin and silence transcription of genes governing cell proliferation, neuronal plasticity, and cardiac hypertrophy. Researchers investigating epigenetic regulation, cancer biology, or neurodegenerative disease pathways rely on this reagent to track endogenous HDAC2 protein levels across treated and untreated cell populations. Supplied at 1 mg/ml in phosphate buffered saline with 0.05% sodium azide at approximately pH 7.2, the 100 µl vial format offers flexibility for titration optimization across multiple blot or slide runs. The polyclonal format increases the likelihood of recognizing multiple epitopes on the target, which can be useful when probing samples where post-translational modification or isoform expression may vary. Storage at 4°C short term, or aliquoted and stored at -80°C for longer term, preserves antibody activity, and freeze-thaw cycles should be minimized.