Anti-HDAC1 Antibody

Histone Deacetylase 1 (HDAC1) is a chromatin-associated epigenetic regulator that removes acetyl groups from lysine residues on histone tails, shaping transcriptional programs in eukaryotic cells. This rabbit polyclonal antibody from Antibodies.com is raised against HDAC1 and has been validated for western blot, immunohistochemistry, immunofluorescence, immunoprecipitation, and chromatin immunoprecipitation workflows.

The reagent is supplied as a 100 µl vial at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol as a cryoprotectant. The unconjugated format offers flexibility for downstream labeling or detection with secondary reagents of choice. The antibody cross-reacts with HDAC1 from human, mouse, and rat origin, enabling comparative studies across commonly used mammalian model systems.

For research use only, this polyclonal reagent supports investigation of histone acetylation dynamics, transcriptional repression complexes, and HDAC inhibitor responses in cancer biology, neurobiology, and stem cell research. Store at -20 degrees C and minimize freeze-thaw cycles to preserve binding activity; the glycerol-based buffer resists ice crystal formation during frozen storage. Aliquot upon first use to limit repeated freeze-thaw events and maintain consistent performance across downstream applications.