Anti-HCLS1-associated protein X-1 Antibody

Raised in rabbit against the human HCLS1-associated protein X-1 (HAX1) target, this polyclonal antibody from Antibodies.com is supplied as a 100 µg vial suitable for Western blot and immunohistochemistry workflows. HAX1 is a mitochondrial and endoplasmic reticulum-associated protein best known for its role in regulating apoptosis and maintaining myeloid cell survival, with loss-of-function mutations linked to autosomal recessive severe congenital neutropenia (Kostmann disease). Researchers studying neutrophil differentiation, mitochondrial signaling, or B-cell receptor pathway components that interact with HCLS1 use this reagent to detect endogenous HAX1 in human cell and tissue samples. The unconjugated format supports flexible downstream detection, including chemiluminescent Western blot on whole-cell lysates and chromogenic IHC on fixed paraffin-embedded sections. For best stability, store the vial at -20°C in working aliquots to limit freeze-thaw cycles of the active antibody preparation.