Anti-HCLS1 Antibody

HCLS1 (Hematopoietic Cell-Specific Lyn Substrate 1) is a cortactin-family actin-binding protein that couples B-cell receptor signaling to cytoskeletal remodeling during lymphocyte activation. Antibodies.com distributes this rabbit polyclonal, unconjugated reagent for western blot and immunohistochemistry on human, mouse, and rat samples.

Supplied as a 100 µl vial at 1 mg/ml in phosphate-buffered saline with 0.05% sodium azide at approximately pH 7.2, the antibody recognizes multiple epitopes on the target, supporting detection of truncated or post-translationally modified HCLS1 isoforms. The reagent is suited for probing endogenous HCLS1 expression in hematopoietic lineages, producing reproducible western blot bands in lymphoid cell lysates and cytoplasmic staining in formalin-fixed spleen, thymus, and lymph node sections.

Each preparation is affinity-purified from rabbit serum and validated against recombinant HCLS1 before release. Store the vial at 4 °C for short-term use; aliquot and store at -20 °C for long-term storage to limit repeated freeze-thaw cycles. The 0.05% sodium azide functions as a microbial preservative within the formulation. This product is intended for research use only and is not for diagnostic or therapeutic applications.