Anti-HAUS3 Antibody

The HAUS3 protein (HAUS Augmin Like Complex Subunit 3) is a core component of the eight-subunit Augmin complex, which amplifies microtubules during mitosis by recruiting the gamma-tubulin ring complex to existing spindle microtubules. This polyclonal antibody from Antibodies.com enables detection of HAUS3 in studies of mitotic spindle assembly, chromosome segregation, and cell division.

Raised in rabbit and unconjugated, the antibody is supplied as an IgG isotype in a 50 microliter liquid format validated for western blot applications. It reacts with human, mouse, and rat samples, supporting comparative work across commonly used mammalian model systems in cell cycle biology. For western blot, the reagent is applied to nitrocellulose or PVDF membranes following SDS-PAGE separation of whole-cell lysates, where HAUS3 is detected at its predicted molecular weight.

Loss or depletion of HAUS3 disrupts Augmin function and leads to spindle defects, reduced microtubule density, and mitotic delay, making reliable detection reagents valuable for ongoing cell division research. This reagent is intended for research use only.