Anti-HAS3 Antibody

HAS3 (Hyaluronan Synthase 3) is a plasma membrane enzyme that catalyzes the synthesis of hyaluronan, a non-sulfated glycosaminoglycan central to extracellular matrix assembly and tissue hydration. This unconjugated rabbit polyclonal antibody from Antibodies.com is raised against the human HAS3 protein and is supplied as a 50 µl volume, suited to Western blot and immunofluorescence workflows on human samples.

Researchers apply the reagent to study hyaluronan biosynthesis in settings such as epithelial-to-mesenchymal transition assays, wound healing models, and tumor microenvironment work, where aberrant HAS3 expression has been linked to cancer cell invasion and stromal remodeling. The polyclonal format enables recognition of multiple epitopes on the target, supporting broader signal capture than a monoclonal reagent when working with denatured lysates or fixed cell preparations. For immunofluorescence, the unconjugated format gives laboratories flexibility to pair the primary with their preferred fluorophore-conjugated secondary antibody. Standard -20 °C storage with working aliquots helps preserve activity across repeated freeze-thaw cycles, and dilutions should be prepared fresh before each experiment.