Anti-HAS1 Antibody

Hyaluronan synthase 1 (HAS1) is a plasma-membrane glycosyltransferase that polymerizes UDP-sugar precursors into hyaluronic acid, a major glycosaminoglycan of the extracellular matrix and synovial fluid. This unconjugated rabbit polyclonal IgG from Antibodies.com is supplied as a 100 µl liquid aliquot, prepared for western blot and immunohistochemistry workflows.

The reagent recognizes the human and mouse HAS1 ortholog, supporting visualization of the full-length synthase in cell lysates, formalin-fixed tissue sections, and primary cell preparations. Researchers apply it to study hyaluronan biosynthesis in fibroblast, keratinocyte, and tumor-derived models, where HAS1 activity contributes to matrix remodeling, wound healing, and tumor-stroma interactions. The unconjugated format allows pairing with HRP-, biotin-, or fluorophore-conjugated secondary reagents of the researcher's choice.

Aliquot on receipt to limit freeze-thaw cycles, store frozen, and protect from light during handling. The polyclonal clonality provides broader epitope coverage than monoclonal alternatives, useful when probing HAS1 across species or examining post-translationally modified forms.