Anti-HAO1 Antibody

Raised in rabbit, this unconjugated polyclonal reagent targets human and mouse hydroxyacid oxidase 1 (HAO1), the peroxisomal enzyme also known as glycolate oxidase. Antibodies.com supplies the preparation as 100 µl of stock solution, intended for western blot and immunohistochemistry workflows. Because no reporter is conjugated, the reagent can be paired with HRP- or fluorophore-tagged secondaries selected by the researcher.

HAO1 is expressed predominantly in liver and kidney, where it converts glycolate to glyoxylate and contributes to endogenous oxalate biosynthesis. It is frequently investigated in studies of glyoxylate pathway flux, peroxisomal function, and primary hyperoxaluria, where loss-of-function studies in mice have shown reduced oxalate synthesis. The reagent cross-reacts with human and mouse samples, supporting work on cell line panels, formalin-fixed tissue sections, and whole-cell lysates.

Store the vial refrigerated at 4 °C to preserve activity; for longer term storage, aliquot and freeze at –20 °C, avoiding repeated freeze-thaw cycles. This product is for research use only and is not approved for diagnostic applications. Each preparation is supplied in a single vial and is validated on relevant positive-control tissues before release.