Anti-HAND1 Antibody

This rabbit polyclonal IgG reagent targets HAND1, a basic helix-loop-helix transcription factor essential for cardiac morphogenesis, extraembryonic mesoderm specification, and trophoblast differentiation. Generated and validated by Antibodies.com, the unconjugated antibody is supplied as 200 µl of ready-to-use reagent and is recommended for Western blot detection of endogenous HAND1 protein in human and mouse samples. HAND1 expression is tightly regulated during development, supporting research in placental biology, cardiac lineage commitment, and embryonic patterning, where HAND1 levels serve as a marker of differentiating trophoblast giant cells and outflow tract progenitors. Storage at -20 °C in single-use aliquots preserves polyclonal antibody activity across multiple experiments; freeze-thaw cycles should be minimized to maintain titer. Pair with an HRP-conjugated anti-rabbit IgG secondary antibody and chemiluminescent substrate for routine immunoblotting of whole-cell or tissue lysates.