Anti-H6PD Antibody

Raised in rabbit against hexose-6-phosphate dehydrogenase (H6PD), this unconjugated polyclonal antibody from Antibodies.com targets the endoplasmic reticulum-resident enzyme that generates NADPH in the ER lumen and supplies reducing equivalents to 11β-hydroxysteroid dehydrogenase type 1. The reagent is supplied as a 100 µl liquid aliquot and is validated for Western blot and immunohistochemistry on human and mouse specimens, making it useful for research into cortisone reductase deficiency, hepatic gluconeogenesis, adipose glucocorticoid activation, and metabolic disease mechanisms.

The antibody recognizes endogenous H6PD in tissue sections and whole-cell lysates without a conjugated reporter, allowing flexible pairing with chromogenic, fluorescent, or HRP-labeled secondary reagents. Researchers working on ER redox balance and pentose-phosphate pathway flux can use it for both analytical Western blot and morphological IHC readouts. For best results, refrigerate the antibody upon arrival and divide into single-use aliquots to avoid repeated freeze-thaw cycles that may reduce binding titer over time.