Anti-H1F0 Antibody

The H1F0 protein, also known as histone H1.0 or H1 zero, is a linker histone that binds internucleosomal DNA and supports higher-order chromatin folding. This rabbit polyclonal primary antibody from Antibodies.com is raised against H1F0 and is validated for Western blot and immunohistochemistry on human samples. Supplied as 100 µl of unconjugated reagent, the antibody targets a key regulator of chromatin condensation and gene silencing, with elevated expression in terminally differentiated cells.

Researchers use it to study nucleosome spacing, DNA methylation-dependent repression, and chromatin remodeling during development and cellular differentiation. The antibody recognizes the ~20 kDa linker histone in whole-cell lysates by western blot and in fixed tissue sections by immunohistochemistry, supporting applications in epigenetics, cancer biology, and stem cell research. For best results, refrigerate the vial and avoid repeated freeze-thaw cycles; aliquot upon first use to preserve activity.