Anti-H. pylori CagA Antibody [10 E 9]

Target the cytotoxin-associated gene A (CagA) protein of Helicobacter pylori with this unconjugated mouse monoclonal reagent from Antibodies.com, cloned from the 10E9 hybridoma line and supplied as a lyophilised 100 µg vial for research use only. CagA is an approximately 120-145 kDa effector protein that the bacterium translocates directly into gastric epithelial cells via its Type IV secretion system, and CagA-positive status distinguishes the more virulent strains linked to gastric adenocarcinoma, MALT lymphoma, and peptic ulcer disease. The IgG2a antibody supports immunodetection workflows including western blot analysis of H. pylori whole-cell lysates and ELISA screening of cultured isolates or clinical biopsy material, with reactivity validated against human-derived H. pylori strains. The lyophilised product form permits ambient shipment and stable refrigerated storage once reconstituted, with aliquots recommended to limit freeze-thaw cycles during routine mucosal immunology and gastric pathogen research applications.