Anti-GZMM Antibody

A rabbit polyclonal reagent targeting granzyme M (GZMM), a serine protease stored in the cytolytic granules of natural killer cells and effector memory CD8+ T cells. The unconjugated antibody is supplied at 1 mg/ml in phosphate buffered saline (PBS) containing 0.05% sodium azide at approximately pH 7.3, making it directly compatible with western blot (WB) workflows run on human, mouse, or rat sample lysates. Each vial of 100 µl supports multiple membrane-probing experiments; aliquoting after first thaw and storing at -20°C preserves reactivity across long-term use, while short-term handling at refrigerated temperatures is acceptable. Antibody reactivity extends across the three species noted in the reactivity panel, supporting comparative immunology studies. The polyclonal host, raised in rabbit, minimizes background overlap when probing mouse or rat primary immune cells, tumor-infiltrating lymphocyte preparations, and whole-tissue extracts relevant to cytotoxic cell biology. Target detection on reducing SDS-PAGE gels aligns with the expected molecular weight of mature granzyme M, and standard chemiluminescent immunoblot protocols using HRP-conjugated secondary antibodies work with this primary reagent. Stored frozen, protected from light, and intended for research use only in academic and translational laboratory settings, the antibody is supplied by Antibodies.com as part of its primary antibody catalog aimed at researchers studying tumor immunity, viral clearance, and granule-exocytosis pathways.