Anti-GUSB Antibody

Raised in rabbit against the GUSB (beta-glucuronidase) protein, this unconjugated polyclonal IgG reagent from Antibodies.com is supplied as 200 µl of liquid in a single vial and validated for Western blot. Beta-glucuronidase is a lysosomal glycosidase that cleaves glucuronic acid residues during glycosaminoglycan catabolism, and the antibody supports detection of endogenous GUSB in human, mouse, and rat samples. Researchers commonly apply it as a lysosomal compartment marker in cell biology workflows and use it to investigate mucopolysaccharidosis type VII (Sly syndrome), a lysosomal storage disorder caused by GUSB deficiency. For best stability, aliquot the 200 µl upon arrival to limit freeze-thaw cycles, store refrigerated at 4 degrees C, and protect from light. The unconjugated format allows flexible pairing with secondary antibodies for chemiluminescent or fluorescent Western blot readouts.