Anti-GUCY1B3 Antibody

This polyclonal reagent from Antibodies.com targets GUCY1B3, the beta-3 subunit of soluble guanylate cyclase (sGC), the heterodimeric nitric oxide receptor that catalyses the conversion of GTP to the second-messenger cyclic GMP in vascular and neuronal signalling cascades. Raised in rabbit and purified as an IgG preparation, the antibody is supplied unconjugated in a 200 µl vial aliquot and is validated for Western blot detection of the human protein in cell and tissue lysates. Researchers investigating NO–cGMP signalling pathways, vascular smooth-muscle relaxation, and cardiovascular or neurological function can incorporate this reagent into research-use-only immunoblotting workflows on human samples.