Anti-Guanylate-binding protein 3 Antibody

This rabbit polyclonal antibody targets Guanylate-binding protein 3 (GBP3), an interferon-induced GTPase that plays a role in cell-autonomous immunity against intracellular bacteria and parasites. Raised in rabbit and supplied as an unconjugated preparation, the reagent is validated for western blot (WB), immunohistochemistry (IHC), and immunofluorescence (IF) workflows on human samples, supporting studies of innate immune signaling, inflammasome regulation, and the tumor-suppressive functions reported for GBP3 in epithelial tissues such as ovarian epithelium. The 100 µl volume is sufficient for multiple staining and blotting experiments, and the polyclonal format broadens epitope coverage for detecting endogenous GBP3 expression in fixed and lysed specimens. Researchers investigating interferon-driven host defense, pathogen restriction, or GBP family biology will find this Antibodies.com reagent a useful tool for probing both baseline and cytokine-induced expression patterns.