Anti-GTF2I Antibody

GTF2I (General Transcription Factor II-I) is a multifunctional transcription factor implicated in signal-dependent gene regulation, B-cell receptor signaling pathways, and neural crest development. Hemizygous deletions involving this gene are linked to Williams-Beuren syndrome, a neurodevelopmental disorder that affects cognition and craniofacial morphogenesis. The Antibodies.com rabbit polyclonal antibody is raised against the GTF2I target and supplied as a 100 µl unconjugated aliquot intended for Western blot (WB) and immunohistochemistry (IHC) workflows. The reagent has been validated for reactivity against human, mouse, and rat samples, supporting translational studies across cultured cell lines, primary tissue sections, and animal model systems. Researchers routinely employ this antibody to probe GTF2I expression in MAPK and calcium-signaling cascades, neuronal differentiation assays, and chromatin immunoprecipitation-style analyses of transcription factor occupancy at inducible promoters.