Anti-GTF2F2 Antibody

This rabbit polyclonal antibody targets GTF2F2 (General Transcription Factor IIF subunit 2), a 28 kDa protein that forms part of the TFIIF complex required for RNA polymerase II to initiate and elongate transcription in eukaryotic cells. Raised in rabbit and supplied unconjugated at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, the 100 µl reagent is validated for western blot, immunohistochemistry, and immunofluorescence workflows on human samples.

GTF2F2, also known as RAP30, partners with RAP74 to recruit Pol II to the pre-initiation complex and stabilize the open promoter during mRNA synthesis. Distributed by Antibodies.com, this Primary Antibody is used to probe TFIIF subunit abundance in nuclear extracts, follow assembly of the pre-initiation complex on chromatin, and map transcription factor distribution in cancer biology and developmental research projects.